Resistance abrogation to murine histoplasmosis induced by antibody

Authors

  • María Lucía Taylor Departamento de Ecología Humana, Facultad de Medicina, Universidad Nacional Autónoma de México, Grupo Multidisciplinario de Micosis (GMM). México, D.F., México
  • Aurora Hernández Departamento de Ecología Humana, Facultad de Medicina, Universidad Nacional Autónoma de México, Grupo Multidisciplinario de Micosis (GMM). México, D.F., México
  • Nora Elizondo Departamento de Ecología Humana, Facultad de Medicina, Universidad Nacional Autónoma de México, Grupo Multidisciplinario de Micosis (GMM). México, D.F., México
  • Jesús Casasola Instituto Nacional de Enfermedades Respiratorias (INER), SS. México, D.F., México
  • María del Rocio Reyes Montes Departamento de Ecología Humana, Facultad de Medicina, Universidad Nacional Autónoma de México, Grupo Multidisciplinario de Micosis (GMM). México, D.F., México
  • Gustavo Acosta Laboratorio de Inmunoquímica, Escuela de Medicina, Instituto Politécnico Nacional. México, D.F., México

DOI:

https://doi.org/10.33885/sf.1986.3.656

Abstract

The course of humoral and cellular responses were followed throughout
infection in experimental histoplasmosis. A possible modulatory role of immune
sera in the cell-mediated immune response, developed during the infection
produced by Histoplasma capsulatum, was also studied. The results demonstrated
that there was a cyclic distribution of cellular and humoral immune responses in
¡nfected mice and that the passive transfer of anti-Histoplasma antibodies
abrogated the survival of mice sublethally ¡nfected, when the sera were transferred
3 h prior to infection. The results obtained from this experimental model suggest that antibody may play a modulating role ¡n cell-mediated responsos in
histoplasmosis.

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How to Cite

Taylor, M. L., Hernández, A., Elizondo, N., Casasola, J., Reyes Montes, M. del R., & Acosta, G. (2016). Resistance abrogation to murine histoplasmosis induced by antibody. Scientia Fungorum, 3(2), 105–117. https://doi.org/10.33885/sf.1986.3.656

Issue

No. 2 (1986): RMM núm. 2 1986

Section

Original papers

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